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Rubber Consultants’ Biotechnology Unit was established in 2008. The state-of-the-art facilities, occupying an area of some 275m2, include purpose-built laboratories and office space as well as a bioinformatics facility that contains a 55-core high-performance Linux computing cluster. The location of Rubber Consultants, just outside London, England, is advantageous due to its close proximity to leading biotechnology centres in the UK and Europe.Main areas of expertise
Biotechnology expertise is available in four broad areas: i) Plant molecular biology, involving investigation of the functions of single genes or complexes of genes; ii) Plant genomics and transcriptomics, including genome sequencing and fine-scale genetic mapping; iii) Plant proteomics, consisting of comprehensive studies of protein structure, expression and function and; iv) Bioinformatics, including sequence assembly, functional annotation of genomic sequence and molecular marker mining.
Rubber Consultants’ Biotechnology services are able to offer the following:
Rubber Consultants Biotechnology services can provide specific assistance in the following disciplines:
Fully equipped laboratories with state-of-the-art instrumentation including:
Use of these instruments and associated equipment can be offered on a bench fee basis. Office space may also be negotiated if required.
The Biotechnology Unit is also able to offer low temperature storage for a wide range of samples in -80oC freezer facility, as well as storage in cryogenic conditions.
UKAS Accredited Testing for the Modified Lowry Latex Protein Assay
Rubber Consultants Biotechnology Unit offers a testing service for the quantification of aqueous extractable protein from natural rubber and its products through the Modified Lowry assay. In-house methods are available for both the American (ASTM D5712-10) and European (EN 455-3:2006) standards. The laboratory was awarded UKAS-accreditation for the in-house method based on ASTM D5712-10 in September 2011, and for the in-house method based on EN 455-3:2006 method in August 2012.
Rubber Consultants staff are experienced in testing of a range of natural rubber products including latex gloves, balloons, exercise bands and others. As a part of the service we are also able to assist with the interpretation of results if required.
Testing for Individual Allergenic Proteins found in Natural Latex
In regard to specific quantification of individual allergenic proteins, we are offering testing for 4 principal Hevea brasiliensis [Hev b] allergenic proteins (Hev b1, Hev b3, Hev b5 and Hev b6.02) in natural rubber and its products derived from latex using FitKit assay following ASTM D7427-08 international standard. The methodology utilizes an immunological method known as immunoenzymetric assay (ELISA) that quantifies amount of target proteins using monoslonal antibodies specific for epitopes on these proteins.
Clonal ID Assessment for Hevea brasiliensis
We have developed clonal identification panel for Hevea brasiliensis based on SNP (single nucleotide polymorphism) molecular markers. It allows confirmation or assignment of clonal identity to planting materials as well as assessment of their uniformity. This is an ideal solution to ensure optimal performance of the plants when they reach their maturity in 5-7 years after planting. Our team is able to handle projects of different sizes with variable numbers of SNPs and samples through use of different genotyping platforms. You can read more on our work in this area here.
Speciation and Adulteration
We offer quantitative assessment and confirmation of species content in a range of products including food and pharmaceuticals. Currently, testing for four species: beef, sheep, pork and chicken. More species-specific assays are being added to the current panel.
We also can develop custom assays on request.
Being affiliated with Malaysia, recognised as a global leader for Halal certification, we will be including these and other methods in our portfolio of test methods for Halal authentication of a variety of products.
If you would like further information regarding any of our areas of expertise, or any related topics not specified here, please do not hesitate to contact us.
Other services offered by Rubber Consultants are:
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Experts in Elastomer & Polymer Testing
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